Hormonal Study for Iraqi Women with Polycystic Ovary syndrome

Authors

  • Hameed Shahad Abbas 1Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq Author
  • Al-Kazazz Fatin Fadhel Mohammed 1Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq Author
  • Rheima Ahmed Mahdi Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq Author

Keywords:

Polycystic ovary syndrome, PCOS, androgenic hormone, LH/FSH ratio

Abstract

 Ovarian polycystic disorder (PCOS) is a common a main hyperandrogenic disorder in which women exhibit hormonal imbalance Ovarian cysts develop when the sex hormones progestin and estrogen are present and are out of balance. This syndrome causes disorders of the female reproductive system due to hormonal disorders, which tiny ovarian cysts on ultrasonography of the ovaries reveal. Among the elements that can impact the disease's clinical signs include obesity and insulin resistance. Therefore, in the current study, we sought to better understand the associations between certain body composition measures and hormone concentrations (including total testosterone, follicle-stimulating hormone, and luteinizing hormone) in a sample of women with and without PCOS. Patients and Methods: 120 blood specimens were collected from Iraqi women attending Private AL-Batoul Hospital for Obstetrics and gynecology. The samples were divided into 60 patients and 60 healthy control groups. Hormones analysis was performed by using an ELFA (enzyme-linked fluorescent assay) method. Results.:The data showed a non-significant alteration in the level of FSH for PCOS patients (p>0.05) in comparison to a healthy control group. According to BMI, a significant difference was between the studied groups, while mean levels of LH and LH/FSH, PRL, and testosterone were increased significantly for both groups of PCOS patients (had child and no child) in comparison to the control group. Conclusion:-PCOS can consider a disorder in the androgenic hormones furthermore the gonadal atropine hormones. 

Downloads

Download data is not yet available.

References

N. Ajmal, S. Z. Khan, and R. Shaikh, "Polycystic ovary

syndrome (PCOS) and genetic predisposition: A review

article," Eur. J. Obstet. Gynecol. Reprod. Biol. X, vol. 3, p.

, 2019, doi: 10.1016/j.eurox.2019.100060.

M. Yesiladali, M. G. K. Yazici, E. Attar, and F. Kelestimur,

"Differentiating Polycystic Ovary Syndrome from

Adrenal Disorders," Diagnostics, vol. 12, no. 9, pp. 1-14,

, doi:10.3390/diagnostics12092045.

S. H. Fatima, M. A. Naeem, A. Ali, and R. Asfar, "Prevalence

of PCOS in Reproductive Age Women in Gujrat City,"

EAS J. Radiol. Imaging Technol., vol. 4, no. 4, pp. 79-83,

, doi: 1O.36349/easjrit.2O22.vO4iO4.OO3.

K.-T. Lu, Y.-C. Ho, C.-L. Chang, K.-C. Lan, C.-C. Wu, and Y.-

T. Su, "Evaluation of Bodily Pain Associated with

Polycystic Ovary Syndrome: A Review of Health-Related

Quality of Life and Potential Risk Factors," Biomedicines,

vol. 10, no. 12, p. 3197, 2022.H. M. Sodeghi et al., "Polycystic Ovary Syndrome: A

Comprehensive Review of Pathogenesis, Management,

and Drug Repurposing," Int. J. Mol. Sci., vol. 23, no. 2,

, doi: 1O.339O/ijms23O2O583.

A. Bongrani et al., "High androgen concentrations in

follicular fluid of polycystic ovary syndrome women,"

Reprod. Biol. Endocrinol., vol. 20, no.1, pp.1-16, 2022, doi:

1186/s12958-022-00959-6.

N. Scannell, L. Moran, E. Mantzioris, S. Cowan, and A. Villani,

"Efficacy, Feasibility and Acceptability of a

Mediterranean Diet Intervention on Hormonal,

Metabolic and Anthropometric Measures in Overweight

and Obese Women with Polycystic Ovary Syndrome:

Study Protocol," Metabolites, vol. 12, no. 4, p. 311, Mar.

, doi: 10.3390/metabo12040311.

N. Boisseau, "Physical Activity During the Perinatal Period:

Guidelines for Interventions During the Perinatal Period

from the French National College of Midwives," J.

Midwifery Womens. Health, vol. 67, no. S1, Nov. 2022, doi:

1111/jmwh.13425.

M. J. Khan, A. Ullah, and S. Basit, "Genetic basis of polycystic

ovary syndrome (PCOS): Current perspectives," Appl.

Clin. Genet., vol. 12, pp. 249-260, 2019, doi:

2147/TACG.S200341.

R. J. Swanson and B. Liu, "Conception and pregnancy," in

Fertility, Pregnancy, and Wellness, Elsevier, 2022, pp. 53-

S. Katta, "Urinary follicle-stimulating hormone glycoform

analysis by automated western blot." Wichita State

University, 2021.

M. I. Borella, C. Chehade, F. G. Costa, L. zaro W. O. De Jesus,

M. Cassel, and S. R. Batlouni, "The brain-pituitary-gonad

axis and the gametogenesis," in Biology and physiology

of freshwater neotropical fish, Elsevier, 2020, pp. 315-

N. L. a Noob, "Old Account".

S. H. H. Al-Musawy, I. E. Al-Saimary, and M. S. Flaifil, "Levels

of cytokines profile in polycystic ovary syndrome," Med.

J. Babylon, vol.15, no. 2, p.124, 2018.

S. Qian et al., "Prolactin variants in human pituitaries and

pituitary adenomas identified with two-dimensional gel

electrophoresis and mass spectrometry," Front.

Endocrinol. (Lausanne)., vol. 9, p. 468, 2018.

N. Sarahian, H. Sarvazad, E. Sajadi, N. Rahnejat, and N.

Eskandari-Roozbahani, "Investigation of common risk

factors between polycystic ovary syndrome and

Alzheimer's disease," 2021.

K. Szosland, P. Paw owicz, and A. Lewi ski, "Prolactin

secretion in polycystic ovary syndrome (PCOS),"

Neuroendocrinol. Lett., vol. 36, no. 1, pp. 53-58, 2015.

I. M. Perovic Blagojevic et al., "Overweight and obesity in

polycystic ovary syndrome: Association with

inflammation, oxidative stress and dyslipidaemia," Br. J.

Nutr., vol. 128, no. 4, pp. 604-612, 2022, doi:

O.1O17/SOOO7114521OO3585.

R. Balasubramanian and W. F. Crowley Jr, "Isolated

gonadotropin-releasing hormone (GnRH) deficiency,"

M. Saei Ghare Naz, M. Mousavi, F. Mahboobifard, A. Niknam,

and F. Ramezani Tehrani, "A Meta-Analysis of

Observational Studies on Prolactin Levels in Women

with Polycystic Ovary Syndrome," Diagnostics, vol.12, no.

, p. 2924, Nov. 2022, doi: 10.3390/diagnostics12122924.

A. Szeliga et al., “Neuroendocrine Determinants of Polycystic

Ovary Syndrome," Int. J. Environ. Res. Public Health, vol.

, no. 5, p. 3089, 2022.

L. S. Mahmood, "Association of Zinc Alpha 2 Glycoproteins

and Heat Shock Protein 70 with Polycystic Ovarian

Syndrome in Iraqi Infertile Women . A Thesis," 1997.

Downloads

Published

2023-02-28

Issue

Section

Articles

How to Cite

Shahad Abbas , H., Fatin Fadhel Mohammed , A.-K., & Ahmed Mahdi , R. (2023). Hormonal Study for Iraqi Women with Polycystic Ovary syndrome. History of Medicine, 9(1). http://13.200.237.241/HOM/index.php/medicine/article/view/809