Hormonal Study for Iraqi Women with Polycystic Ovary syndrome
Keywords:
Polycystic ovary syndrome, PCOS, androgenic hormone, LH/FSH ratioAbstract
Ovarian polycystic disorder (PCOS) is a common a main hyperandrogenic disorder in which women exhibit hormonal imbalance Ovarian cysts develop when the sex hormones progestin and estrogen are present and are out of balance. This syndrome causes disorders of the female reproductive system due to hormonal disorders, which tiny ovarian cysts on ultrasonography of the ovaries reveal. Among the elements that can impact the disease's clinical signs include obesity and insulin resistance. Therefore, in the current study, we sought to better understand the associations between certain body composition measures and hormone concentrations (including total testosterone, follicle-stimulating hormone, and luteinizing hormone) in a sample of women with and without PCOS. Patients and Methods: 120 blood specimens were collected from Iraqi women attending Private AL-Batoul Hospital for Obstetrics and gynecology. The samples were divided into 60 patients and 60 healthy control groups. Hormones analysis was performed by using an ELFA (enzyme-linked fluorescent assay) method. Results.:The data showed a non-significant alteration in the level of FSH for PCOS patients (p>0.05) in comparison to a healthy control group. According to BMI, a significant difference was between the studied groups, while mean levels of LH and LH/FSH, PRL, and testosterone were increased significantly for both groups of PCOS patients (had child and no child) in comparison to the control group. Conclusion:-PCOS can consider a disorder in the androgenic hormones furthermore the gonadal atropine hormones.
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References
N. Ajmal, S. Z. Khan, and R. Shaikh, "Polycystic ovary
syndrome (PCOS) and genetic predisposition: A review
article," Eur. J. Obstet. Gynecol. Reprod. Biol. X, vol. 3, p.
, 2019, doi: 10.1016/j.eurox.2019.100060.
M. Yesiladali, M. G. K. Yazici, E. Attar, and F. Kelestimur,
"Differentiating Polycystic Ovary Syndrome from
Adrenal Disorders," Diagnostics, vol. 12, no. 9, pp. 1-14,
, doi:10.3390/diagnostics12092045.
S. H. Fatima, M. A. Naeem, A. Ali, and R. Asfar, "Prevalence
of PCOS in Reproductive Age Women in Gujrat City,"
EAS J. Radiol. Imaging Technol., vol. 4, no. 4, pp. 79-83,
, doi: 1O.36349/easjrit.2O22.vO4iO4.OO3.
K.-T. Lu, Y.-C. Ho, C.-L. Chang, K.-C. Lan, C.-C. Wu, and Y.-
T. Su, "Evaluation of Bodily Pain Associated with
Polycystic Ovary Syndrome: A Review of Health-Related
Quality of Life and Potential Risk Factors," Biomedicines,
vol. 10, no. 12, p. 3197, 2022.H. M. Sodeghi et al., "Polycystic Ovary Syndrome: A
Comprehensive Review of Pathogenesis, Management,
and Drug Repurposing," Int. J. Mol. Sci., vol. 23, no. 2,
, doi: 1O.339O/ijms23O2O583.
A. Bongrani et al., "High androgen concentrations in
follicular fluid of polycystic ovary syndrome women,"
Reprod. Biol. Endocrinol., vol. 20, no.1, pp.1-16, 2022, doi:
1186/s12958-022-00959-6.
N. Scannell, L. Moran, E. Mantzioris, S. Cowan, and A. Villani,
"Efficacy, Feasibility and Acceptability of a
Mediterranean Diet Intervention on Hormonal,
Metabolic and Anthropometric Measures in Overweight
and Obese Women with Polycystic Ovary Syndrome:
Study Protocol," Metabolites, vol. 12, no. 4, p. 311, Mar.
, doi: 10.3390/metabo12040311.
N. Boisseau, "Physical Activity During the Perinatal Period:
Guidelines for Interventions During the Perinatal Period
from the French National College of Midwives," J.
Midwifery Womens. Health, vol. 67, no. S1, Nov. 2022, doi:
1111/jmwh.13425.
M. J. Khan, A. Ullah, and S. Basit, "Genetic basis of polycystic
ovary syndrome (PCOS): Current perspectives," Appl.
Clin. Genet., vol. 12, pp. 249-260, 2019, doi:
2147/TACG.S200341.
R. J. Swanson and B. Liu, "Conception and pregnancy," in
Fertility, Pregnancy, and Wellness, Elsevier, 2022, pp. 53-
S. Katta, "Urinary follicle-stimulating hormone glycoform
analysis by automated western blot." Wichita State
University, 2021.
M. I. Borella, C. Chehade, F. G. Costa, L. zaro W. O. De Jesus,
M. Cassel, and S. R. Batlouni, "The brain-pituitary-gonad
axis and the gametogenesis," in Biology and physiology
of freshwater neotropical fish, Elsevier, 2020, pp. 315-
N. L. a Noob, "Old Account".
S. H. H. Al-Musawy, I. E. Al-Saimary, and M. S. Flaifil, "Levels
of cytokines profile in polycystic ovary syndrome," Med.
J. Babylon, vol.15, no. 2, p.124, 2018.
S. Qian et al., "Prolactin variants in human pituitaries and
pituitary adenomas identified with two-dimensional gel
electrophoresis and mass spectrometry," Front.
Endocrinol. (Lausanne)., vol. 9, p. 468, 2018.
N. Sarahian, H. Sarvazad, E. Sajadi, N. Rahnejat, and N.
Eskandari-Roozbahani, "Investigation of common risk
factors between polycystic ovary syndrome and
Alzheimer's disease," 2021.
K. Szosland, P. Paw owicz, and A. Lewi ski, "Prolactin
secretion in polycystic ovary syndrome (PCOS),"
Neuroendocrinol. Lett., vol. 36, no. 1, pp. 53-58, 2015.
I. M. Perovic Blagojevic et al., "Overweight and obesity in
polycystic ovary syndrome: Association with
inflammation, oxidative stress and dyslipidaemia," Br. J.
Nutr., vol. 128, no. 4, pp. 604-612, 2022, doi:
O.1O17/SOOO7114521OO3585.
R. Balasubramanian and W. F. Crowley Jr, "Isolated
gonadotropin-releasing hormone (GnRH) deficiency,"
M. Saei Ghare Naz, M. Mousavi, F. Mahboobifard, A. Niknam,
and F. Ramezani Tehrani, "A Meta-Analysis of
Observational Studies on Prolactin Levels in Women
with Polycystic Ovary Syndrome," Diagnostics, vol.12, no.
, p. 2924, Nov. 2022, doi: 10.3390/diagnostics12122924.
A. Szeliga et al., “Neuroendocrine Determinants of Polycystic
Ovary Syndrome," Int. J. Environ. Res. Public Health, vol.
, no. 5, p. 3089, 2022.
L. S. Mahmood, "Association of Zinc Alpha 2 Glycoproteins
and Heat Shock Protein 70 with Polycystic Ovarian
Syndrome in Iraqi Infertile Women . A Thesis," 1997.
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