An animal study of the histo-physiological influence of green tea extract on the lead nitrate-treated heart
Keywords:
Green tea extract, lead nitrates, troponin-I, calcium, heart, ratsAbstract
Background: Green tea extracts have shown an interesting influence on human body health. The lead from higher ecological pollution and industrialized usage has become a danger to community health. The existing work aims to scrutinize the histo-physiological changes of green tea extract on the rats’ hearts after treatment with lead nitrates. Methods: The female rats were erratically divided into four groups of six rats. The first control group received distilled drinking water. The second group received treatment with an extract of green tea solution. The third group received a lead nitrates treatment, while the fourth received an 8-week treatment of a green tea extract, lead nitrates, and distilled water mixture. After the animals were killed, blood samples were taken to quantify troponin-I and calcium. All the rats then had their hearts histologically examined. Results: The primary finding of this study was that rats treated with green tea and lead nitrate had higher troponin-I levels in their blood than rats treated with lead nitrate alone. The heart's histopathological sections also showed that rats treated with lead suffered greater damage and adverse morphological changes than rats treated with green tea extract and lead nitrates. The study demonstrated how well green tea extract protects the heart from harm caused by lead nitrates. Conclusion|: In terms of troponin-I serum levels and histological changes in the rats' heart tissues, the green tea extract revealed good protective effects against cardiac damage caused by the harmful effects of lead nitrates.
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