Effect of infection with the giant liver fluke (Fasciola gigantica) on the Superoxide dismutase (SOD) in liver tissue naturally infected with parasite
Keywords:
Superoxide dismutase, Fasciola giganticaAbstract
The current study was conducted with the aim of assessing the level of antioxidant (SOD) in the tissues of worms, and tissues of liver cows infected with Fasciola gigantica and uninfected livers in order to determine the effects of Fasciola gigantica infection. Through the current study, which extends from 12/12/2021 to 30/7/2022, 1422 cows and sheep livers were examined from butcher shop in Baquba city, Diyala province. One hundred and seventy four of livers for cows, and 1248 livers of sheep were collected with 14 non-infected liver in current study. In this study, 25 liver samples were infected with Fasciola gigantica belong to cows with absence of infection in sheep. Pieces of infected and non infected livers (14 non infect liver) samples were taken and homogenized. The activity of the enzyme Superoxide dismutase (SOD) was measured by ELISA. The results of the current study showed that there is a clear significant difference in the concentration of this enzyme for each of worms and infected liver (P<0.05). The results also showed that there is a significant difference between the infected group and the control group in all the studied areas (P <0.05).
Downloads
References
Al-Juboury, M. M. O. (2008). Epidemiological study vitality
about infection final and intermediate hosts of Fasciola
gigantica in Karbala. M. Sc. Thesis, Educ. Coll. Unvi.
Karbala. 2008, 79 (In Arabic).
Bahrami S, Esmaeilzadeh S, Oryan A. (2014). Role of oxidative
stress in concomitant occurrence of Fasciola giganticaand
leiomyoma in cattle.Vet. Parasito^OSO-^yAS-EO.
Biswas T, Ghosh DK, Mukherjee N, Ghosal J (1997) Lipid
peroxidation of erythrocytes in visceral leishmaniasis. J
Parasitol 83:151-152.
Dalton, J. P. (1999). Fasciolosis, CABI publishing, Dublin.
Ibrahim, N. (2017). Fascioliasis: systematic review. Advances
in Biol. Res., 11(5): 278-285.
Itagaki, T. ; Hayashi, K. and Oharim Y.(2O22). The causative
agents of fascioliasis in animals and humans:
Parthenogenetic Fasciola in Asia and other regions,
https://doi.Org/10.1016/i.meegid.2022.105248.
Jabbar,K. D. (2022). Biochemical Evaluation of Antioxidant
Enzyme Activities and Lipid Peroxidation Level Associated
with Liver Enzymes in Patients with Fascioliasis. Archives
of Razi Institute, Vol. 77, No. 3 (2022) 1067-1073.
Kurnianto , H.;Siti Zubaidah Ramanoonl , Nor Azlina Abdul
Aziz3 and Soedarmanto Indarjulianto4 (2022).
Prevalence, risk factors, and infection intensity of
fasciolosis in dairy cattle in Boyolali, Indonesia.
Available at www.veterinaryworld.org/Vol.15.
Mendes E.A, Mendes T.A, dos Santos S.L, Menezes-Souza D,
Bartholomeu D.C,Martins I.V, Silva L.M,Lima W.D.S.(2013).
Expression of IL-4, IL-10 and IFN-gamma in the liver tissue
of cattle that are naturally infected with Fasciola
hepatica. Vet. Parasitofi95(V2y.']77-'82.
Mikaeel, F. B. (2020). Prevalence of Fasciola hepatica in Goatsand Sheep by Using ELISA in Sera and Milk in Duhok, Iraq.
The Iraqi Journal of Veterinary Medicine, 44 (2): 113-119.
Mittra, B., Laranjeira-Silva, M. F., Miguel, D. C., de Menezes,
J. P. B., & Andrews, N. W. (2017). The iron-dependent
mitochondrial superoxide dismutase SODA promotes
Leishmania virulence. Journal of Biological Chemistry,
(29), 12324-12338.
Mpisana, Z; Jaja, I. F; Byaruhanga, C. and Marufu, M. C. (2022).
Body condition scores, fluke intensity, liver pathology, and
carcass quality of different dairy cattle genotypes infected
with Fasciola species at high throughput abattoirs in South
Africa, Parasitology Research121:1671-1682.
Nabi S, Tanveer S, Ganie SA (2017) Glutathione-s-transferase,
superoxide dismutase (GST, SOD) levels, protein content and
lipid peroxidation in Schizothorax plagiostomus under the
infection of Pomphorhynchus in NaIlah Sukhnag of Kashmir
Valley. Pak J Biol Sci 20(9):442-446.
Olivares-Ferretti, P.,•Orellana-Caceres, J. J. Salazar, L. A. and
Fonseca-Salamanca, F. (2022). Fascioliasis prevalence in
livestock from abattoirs in southern Chile.
http://dx.doi.org/10.4067/S0719-81322022000100029.
Raoof, H. S. ; Marif, H. F. ; Rahman, H. S. ; Sheikh, M. O. B.
and Ahmed, A. M. S. (2020). Molecular characterization
and phylogenetic analysis of Fasciola species in sheep
and goats in Sulaymaniyah Province, Northern Iraq.
Journal homepage www.jzs.uos.edu.krd.
Rubio, C., Escribano, D., Hernandez, J., Ceron, J.,
Tvarijonaviciute, A., & Martinez-Subiela, S. (2019). Blood
Biomarkers of Oxidative Stress in Human and Canine
Leishmaniosis Oxidative Stress in Microbial Diseases
(pp. 21-31): Springer.
Serarslan, G., Yilmaz, H., & Sogut, S. (2005). Serum
antioxidant activities, malondialdehyde and nitric oxide
levels in human cutaneous leishmaniasis. Clinical and
Experimental Dermatology: Experimental dermatology,
(3), 267-271.
Shahatha, S.S.; Ayyed, I.M. and Mousa, M.O. (2021). An
epidemiological and therapeutic study of Sarcoptes
scabiei parasite in cows of Anbar province, Iraq. Article
, Volume 36, Issue 1, Winter 2022, Page 103-109.
Smyth JD, Barret NJ (1980) Procedures for testing the
viability of human hydatid cyst following surgical
removal, especially after chemotherapy. Trans R Soc
Trop Med Hyg 74(5):649-652.
Wagari, A. (2021). A Review on Infectious Bursal Disease in
Poultry College of Medical and Health Sciences, School
of Veterinary Medicine, Wollega University, P. O. Box
, Nekemte, Ethiopia.
M. Desai,M. ; Chang,T. ; Wang,H; Banigesh,A.;Arti Dhar,A.
and Liu,J. (2010). Oxidative stress and aging Is
methylglyoxal the hidden enemy. Publication: Canadian
Journal of Physiology and Pharmacology
https://doi.org/10.1139/Y10-001
Fukai, T and Ushio-Fukai, M (2011). Superoxide dismutases:
role in redox signaling, vascular function, and
diseases. Antioxid Redox Signal15,1583-606.
Downloads
Published
Issue
Section
License
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.