Association of Metabolic Syndrome Components among patients with psoriasis in Duhok (Iraq

Abstract

 Background: Psoriasis is thought to be one of the systemic diseases with possible health consequences beyond the skin; studies suggesting psoriasis relation to metabolic syndrome are debatable. Objectives: This work sought to determine whether the components of psoriasis and metabolic syndrome are related. Methods: The research included 117 individuals with recognized psoriasis, ranging in age from 18 to 65. A total of three groups have been created based on their PASI scores: there were 33 moderate cases, 80 mild cases, and 4 severe instances of psoriasis. Body height, blood pressure, weight, waist circumference (WC), total cholesterol, blood glucose, HDL-c, uric acid, LDL-c, and triglycerides were examined in each instance. Results: When put to comparison with the mild group, the moderate to severe psoriasis group had considerably high triglycerides (p=0.012). Of the patients examined, 75.2% were obese and overweight and 71.8% have been centrally obese. Psoriasis was shown to be positively correlated with dyslipidemia (triglycerides > 150mg/dl, 34.2%; HDL-c 40mg/dl, 24.8%); 59% of the patients had a cluster of 2 or more metabolic syndrome components, while 17.90% did not have these symptoms. Conclusion: The findings show that over two-thirds of cases were obese or overweight and that more than half (59.0%) exhibited at least two signs of metabolic syndrome.