Prevalence of Insulin Resistance Among Apparently Healthy Medical Students of College of Health and Medical Technology – Shekhan
Keywords:
insulin resistance, medical students, obesityAbstract
Background: Insulin resistance is an impairment of insulin biological action with reduction in muscle and adipose tissue sensitivity to insulin level resulting in decreased glucose uptake in the muscle and increased glucose production from liver causing hyperglycemia in both the fasting and postprandial states. Worldwide, the prevalence of insulin resistance varies between 15.5% to 46.5% among adults. Objectives: The present study was conducted with the objective to determine the relationship between insulin resistance and Body mass index ,waist circumference , residency and alcohol consumption among apparently healthy Shekhan medical students. Materials and Methods: The study was carried out as across sectional study among 200 Shekhan medical students ranging from 18- 39 years old who were randomly selected from the student population. Under strict aseptic precautions blood samples was collected from all the participants, the serum was investigated for glucose, insulin, and lipid parameters (cholesterol, triglyceride, HDL-C, LDL-CH). Insulin resistance was determined using (HOMA-IR). Results: The prevalence of insulin resistance was 21.50% among Shekhan medical students. The mean homeostatic model assessment was higher in those married, older than 25years, overweight and obese. The mean BMI and WC were significantly higher in those with HOMA IR >3.0 as well as the majority of those with IR were leaving in urban area. Moreover, there was a positive and significant correlation of insulin resistance with BMI, WC and residency (P < 0.05). Conclusion: Prevalence of insulin resistance among the Shekhan medical students was high ranging about 21.50% especially obese female leaving in urban area
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References
Artese, A., Stamford, B.A. and Moffatt, R.J.,
Cigarette smoking: an accessory to
the development of insulin
resistance. American journal of lifestyle
medicine, 13(6), pp.602-605.
Al-Farai, H.H., Al-Aboodi, I., Al-Sawafi, A., AlBusaidi, N. and Woodhouse, N., 2014. Insulin
resistance and its correlation with risk factors
for developing diabetes mellitus in 100 omani
medical students. Sultan Qaboos University
Medical Journal, 14(3), p.e393.
Al-Sejari, M., 2017. Sociocultural
characteristic, lifestyle, and metabolic risk
factors among a sample of Kuwaiti male
university students. American Journal of
Men's Health, 11(2), pp.308-317.
Beckerman, M., Harel, C., Michael, I., Klip, A.,
Bilan, P.J., Gallagher, E.J., LeRoith, D.,
Lewis, E.C., Karnieli, E. and Levenberg, S.,
GLUT4-overexpressing engineered
muscle constructs as a therapeutic platform to
normalize glycemia in diabetic mice. Science
advances, 7(42), p.eabg3947.
Barbosa, J.B., Santos, A.M.D., Barbosa, M.M.,
Barbosa, M.M., Carvalho, C.A.D., Fonseca,
P.C.D.A., Fonseca, J.M., Barbosa,
M.D.C.L., Bogea, E.G. and Silva,
A.A.M.D., 2016. Metabolic syndrome,
insulin resistance and other cardiovascular
risk factors in university students. Ciência &
saúde coletiva, 21, pp.1123-1136.
Biagetti, B., Aulinas, A., Casteras, A., PérezHoyos, S. and Simó, R., 2021. HOMA-IR
in acromegaly: a systematic review and
meta-analysis. Pituitary, 24(2), pp.146-
Saadi, A.B., Salih, S.F. and Mosa, A.A.,
(2022). Serum magnesium levels among
type 2 diabetic patients and prediabetic
subjects in Duhok city/Iraq. Duhok
Medical Journal, 16(1), pp.1-14.
Charpe, C., Biswas, S. S., & Jain, V. (2017).
Prevalence of Insulin Resistance and its
Association with Obesity and Alcoholism
in Male Medical Students of Bhopal. Int.
J. Life. Sci. Scienti. Res, 3(3), 1094-1099.
Chetna Charpe1, S. S. B. V. J., 2017. Chetna
Charpe1, S. S. B. V. J., 2017. Prevalence
of Insulin Resistance and its association
with obesity and alcholism in male
medical students of bhopal.. Int. J. Life.
Sci. Scienti. Res.,
Elfaki, F.A., Mukhayer, A.I., Moukhyer,
M.E., Chandika, R.M. and Kremers, S.P.,
Prevalence of Metabolic Syndrome
among Early Adolescents in Khartoum
State, Sudan. International Journal of
Environmental Research and Public
Health, 19(22), p.14876.
Fahed, M., Abou Jaoudeh, M.G., Merhi, S.,
Mosleh, J.M.B., Ghadieh, R., Al Hayek, S.
and El Hayek Fares, J.E., 2020. Evaluation of
risk factors for insulin resistance: a cross
sectional study among employees at a private
university in Lebanon. BMC endocrine
disorders, 20(1), pp.1-14.
Freeman, A.M. and Pennings, N., 2021. Insulin
Resistance. 2021 Jul 10. StatPearls [Internet].
Treasure Island (FL): StatPearls Publishing.
Gobato, A.O., Vasques, A.C.J., Zambon, M.P.,
Barros Filho, A.D.A. and Hessel, G., 2014.
Metabolic syndrome and insulin resistance in
obese adolescents. Revista paulista de
pediatria, 32, pp.55-59.
Goel, N., Khandelwal, V., Pandya, K. and
Kotwal, A., 2015. Alcohol and tobacco use
among undergraduate and postgraduate
medical students in India: A multicentric
cross-sectional study. Central Asian
journal of global health, 4(1).
Ibrahim, I. and Salih, S., 2022. Serum Irisin
In Individuals with Type 2 Diabetes
Mellitus and Prediabetes in Duhok
City. Journal of Life and Bio Sciences
Research, 3(02), pp.59-64.
Khan, Z.N., Assir, M.Z.K., Shafiq, M.,
Chaudhary, A.E.G. and Jabeen, A., 2016.
High prevalence of preobesity and obesity
among medical students of Lahore and its
relation with dietary habits and physical
activity. Indian journal of endocrinology
and metabolism, 20(2), p.206.
Mohammed, A.M., Al-Rawi, R.A.,
Abdulmajeed, B.Y. and Ayoub, N.I.,
The relationship between blood
pressure and body mass index among
primary-school children. Medical
Journal of Babylon, 19(3), p.482.Parajuli, K., Narasannavar, A. and
Shivaswamy, M.S., 2019. Obesity and
Overweight Among Medical College
Students in Belagavi, Karnataka. J
Health Educ Res Dev, 7(301), p.2.
Qaid, M.M. and Abdelrahman, M.M., 2016.
Role of insulin and other related hormones
in energy metabolism—A review. Cogent
Food & Agriculture, 2(1), p.1267691.
Suleiman, R.R. and Sulaiman, D.M., 2018.
Studying levels of homocysteine in
diagnosed cases of polycystic ovary
syndrome. Medical Journal of
Babylon, 15(4), p.291.
Wolosowicz, M., Lukaszuk, B. and
Chabowski, A., 2020. The causes of insulin
resistance in type 1 diabetes mellitus: is
there a place for quaternary
prevention?. International Journal of
Environmental Research and Public
Health, 17(22), p.8651.
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