The SARS-CoV2 effect on renal function in patients after recovery from COVID-19
Keywords:
COVID-19, Creatinine, Renal, SARS-CoV-2, Urea.Abstract
Objective: SARS-CoV-2 infects the kidneys through Angiotensin Converting Enzyme 2 (ACE2), which is overexpressed in comparison to some other organs. Thus, leads imbalance of renal function. Methods:
his study involved four groups (G1: Healthy group, G2:Cardiovascular illness group, G3: Respiratory illness group, And G4: recovery from COVID-19 group). Collected blood samples from the COVID-19 epidemic center in Salah Al-din general hospital, with confirmed recovery from COVID-19. Results: The findings of this study demonstrated a significant difference in urea and creatinine concentrations in the G2 and G3 groups compared to the Healthy group in both genders. But the no statistical significance between G4 and Healthy group. and the other hand found a low significance in the concentration of potassium in G2, and G3 compared with the Healthy group in both genders. While showing a high significance in the concentration of potassium in the G4 compared with the Healthy group in males, but no significance in G4 in females. Conclusion: The renal disorders in patients after recovery from COVID-19, can lead to renal damage and impaired function. Maybe the reason is due to the SARS-CoV2 effect on renal epithelial cells and proximal tubule damage.
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