Relationship between CT-finding, degree of lung involvement and oxygen saturation in hospitalized patients with COVID19

Authors

  • Haider Ala Hussian College of medicine, University of Babylon, Iraq Author
  • Alsultani Fadhil Kadhim Jasim Merjan teaching hospital Babylon/ Iraq Author
  • Mohan Usama Khalaf Merjan teaching hospital Babylon/ Iraq Author

Keywords:

CT-finding; hospitalized patients; COVID19

Abstract

 objective :With the pandemic of COVID-19 and increasing number of patients all over the world including our country (Iraq) , there is a need to study the relationship between the CT_ finding and the saturation of oxygen in hospitalized patient.Methods :A prospective study involved hospitalized patients (diagnosed by PCR) admitted to metjan teaching hospital between 15 july and 30 October 2020 , history was taken regarding age, gender, symptoms ,presence of comorbidities , body mass index was measured ,CT was done to all patients ,degree of lung involvement was assessed for every patient , O?saturation was measured.Results :cross sectional study involved 150 patients, (40.7%) females and (59.3%) males, (76.0%) had history of contact , (4.7%) had history of travel, symptoms were fever (81.3%) , cough ( 64%) , fatigue (56.7%) , shortness of breath ( 44.7%) , chest pain ( 27.3%), headache ( 26.7% ),sore throat (18.0%) , loss of smell and taste (11.3%) , abdominal pain ( 4%),comorbidities were as follows hypertension (39.3%) , diabetes (33.3%) ,ischemic heart disease ( 4.0%) , rheumatoid arthritis (1.3%) , smoker (8.7%). Regarding CT-finding (99.3%) had ground glass appearance , bilateral lesion occurred in 94%, 23.3% crazy paving and 14% had consolidation , (0.67%) had gradel , (26%) grade 2 , (32.67%) grade 3 ,(30.67%) grade 4 and (10%) grade 5, (13.33%) had normal oxygen saturation, (11.33%) mild hypoxia, (23.33%) moderate hypoxia , (52%) had severe hypoxia.Conclusion : There was significant association between involvement of lung tissue by CT and body mass index ,also significant association between lung involvement and oxygen saturation ,while there was no significant association between lung involvement with respiratory rate and gender. 

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References

Alon T, Doepke M, Olmstead-Rumsey J, &

Tertilt M. (2020). The impact of COVID-

on gender equality. National Bureau of

economic research.

https://www.nber.org/papers/w26947

Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, AlRabiah FA, Al-Hajjar S et al. (2013)

Epidemiological, demographic, and

clinical characteristics of 47 cases of

Middle East respiratory syndrome

coronavirus disease from Saudi Arabia: a

descriptive study. The Lancet infectious

diseases 13 (9): 752-761. DOI:

https://doi.org/10.1016/S1473-

(13)70204-4

Bai HX, Hsieh B, Xiong Z, Halsey K, Choi JWet

al. (2020) Performance of radiologists in

differentiating COVID-19 from nonCOVID-19 viral pneumonia at chest CT.

Radiology 296 (2): E46-E54. DOI:

https://doi.org/10.1148/radiol.20202008

Banerjee A, Kulcsar K, Misra V, Frieman M, &

Mossman K (2019) Bats and

coronaviruses. Viruses 11 (1): 41. DOI:

https://doi.org/10.3390/vll010041

Berrizbeitia LD (2014) The Lower Limit of

Normal in the evaluation of pulmonary

function. Heart & Lung: The Journal of

Cardiopulmonary and Acute Care 43 (4):

-268. DOI:

https://doi.org/10.1016/j.hrtlng.2014.04.

Oil

Booth CM, Matukas LM, Tomlinson GA,

Rachlis AR, Rose DB et al. (2003)

Clinical features and short-term outcomes

of 144 patients with SARS in the greater

Toronto area. Jama 289 (21): 2801-2809.

DOI:

https://doi.org/10.1001/jama.289.2LJO

C3O885

Burke RM, Midgley CM, Dratch A, Fenstersheib

M, Haupt T et al. (2020) Active

monitoring of persons exposed to patients

with confirmed COVID-19— United

States, January—February 2020.

Morbidity and Mortality Weekly Report

(9): 245-246. DOI:

https://doi.org/10.15585%2Fmmwr.mm

el

Chan JF-W, Yuan S, Kok K-H, To KK-W, Chu

H et al. (2020) A familial cluster of pneumonia associated with the 2019 novel

coronavirus indicating person-to-person

transmission: a study of a family cluster.

The lancet 395 (10223): 514-523. DOI:

https://doi.org/10.1016/S0140-

(20)30154-9

Chen N, Zhou M, Dong X, Qu J, Gong F et al.

(2020) Epidemiological and clinical

characteristics of 99 cases of 2019 novel

coronavirus pneumonia in Wuhan, China:

a descriptive study. The lancet 395

(10223): 507-513. DOI:

https://doi.org/10.1016/S0140-

(20)30211-7

De Haan CA, Kuo L, Masters PS, Vennema H, &

Rottier PJ (1998) Coronavirus particle

assembly: primary structure requirements

of the membrane protein. Journal of

virology 72 (8): 6838-6850. DOI:

https://doi.org/10.1128/jvi.72.8.6838-

1998

Fu F, Lou J, Xi D, Bai Y, Ma G et al. (2020) Chest

computed tomography findings of

coronavirus disease 2019 (COVID-19)

pneumonia. European radiology 30 (10):

-5498. DOI:

https://doi.org/10.1007/s00330-020-

-8

Giannakoulis VG, Papoutsi E, & Siempos II

(2020) Effect of cancer on clinical

outcomes of patients with COVID-19: a

meta-analysis of patient data. JCO global

oncology 6: 799-808. DOI:

https://doi.org/10.1200/go.20.00225

Guan W-j, Ni Z-y, Hu Y, Liang W-h, Ou C-q et

al. (2020) Clinical characteristics of

coronavirus disease 2019 in China. New

England journal of medicine 382 (18):

-1720. DOI:

https://doi.org/10.1056/NEJMoa200203

Hales CM, Fryar CD, Carroll MD, Freedman

DS, & Ogden CL (2018) Trends in obesity

and severe obesity prevalence in US youth

and adults by sex and age, 2007-2008 to

-2016. Jama 319 (16): 1723-1725.

DOI:

https://doi.org710.1001/jama.2018.3060

Ho S, Mak JW-Y, Jacqueline S, Grace L, Frankie

L et al. (2020). Incidence and clinical

course of COVID-19 in patients with

rheumatologic diseases: a population¬

based study. Seminars in Arthritis and

Rheumatism. 50(5) (pp. 885-889).

Elsevier.

https://doi.org/10.1016/j.semarthrit.2020

.07.012

Huang C, Wang Y, Li X, Ren L, Zhao J et al.

(2020) Clinical features of patients

infected with 2019 novel coronavirus in

Wuhan, China. The lancet 395 (10223):

-506. DOI:

https://doi.org/10.1016/S0140-

(20)30183-5

Hui DS, & Zumla A (2019) Severe acute

respiratory syndrome: historical,

epidemiologic, and clinical features.

Infectious Disease Clinics 33 (4): 869-889.

DOI:

https://doi.Org/10.1016/j.idc.2019.07.001

Johnson JD, & Theurer WM (2014) A stepwise

approach to the interpretation of pulmonary

function tests. American family physician 89

(5): 359-366. URL:

https://www.aafp.org/pubs/afjp/issues/2014/

/p359.html

Kang Z, Luo S, Gui Y, Zhou H, Zhang Z et al.

(2020) Obesity is a potential risk factor

contributing to clinical manifestations of

COVID-19. International journal of

obesity 44 (12): 2479-2485. DOI:

https://doi.org/10.1038/s41366-020-

-2

Kim H (2020) Outbreak of novel coronavirus

(COVID-19): What is the role of

radiologists? (Vol. 30). Springer. DOI:https://doi.org/10.1007/s00330-020-

-2

Koetzner CA, Parker MM, Ricard CS, Sturman

LS, & Masters P (1992) Repair and

mutagenesis of the genome of a deletion

mutant of the coronavirus mouse hepatitis

virus by targeted RNA recombination.

Journal of virology 66 (4): 1841-1848.

DOI:

https://doi.org/10.1128/jvi.66.4.1841-

1992

Lechien JR, Chiesa Estomba CM, Place S, Van

Laethem Y, Cabaraux P et al. (2020) Clinical

and epidemiological characteristics of 1420

European patients with mild to moderate

coronavirus disease 2019. Journal of internal

medicine 288 (3): 335-344. DOI:

https://doi.org/10.1111/joim.13089

Li B, Yang J, Zhao F, Zhi L, Wang X et al. (2020)

Prevalence and impact of cardiovascular

metabolic diseases on COVID-19 in

China. Clinical research in cardiology

: 531-538. DOI:

https://doi.org/10.1007/s00392-020-

-9

Linton NM, Kobayashi T, Yang Y, Hayashi K,

Akhmetzhanov AR et al. (2020)

Incubation period and other

epidemiological characteristics of 2019

novel coronavirus infections with right

truncation: a statistical analysis of publicly

available case data. Journal of clinical

medicine 9 (2): 538. DOI:

https://doi.org/10.3390/jcm9020538

Liu J, Li S, Liu J, Liang B, Wang X et al. (2020)

Longitudinal characteristics of

lymphocyte responses and cytokine

profiles in the peripheral blood of SARSCoV-2 infected patients. EBioMedicine

: 1-9. DOI:

https://doi.org/10.1016/j.ebiom.2020.10

Liu Y, Gayle AA, Wilder-Smith A, & Rocklov J

(2020) The reproductive number of

COVID-19 is higher compared to SARS

coronavirus. Journal of travel medicine: 1-

DOI:

https://doi.org/10.1093/jtm/taaa021

Menni C, Valdes AM, Freidin MB, Sudre CH,

Nguyen LH et al. (2020) Real-time

tracking of self-reported symptoms to

predict potential COVID-19. Nature

medicine 26 (7): 1037-1040. DOI:

https://doi.org/10.1038/s41591-020-

-2

Moein ST, Hashemian SM, Mansourafshar B,

Khorram Tousi A, Tabarsi P et al. (2020)

Smell dysfunction: a biomarker for

COVID 19. International forum of allergy

& rhinology 10 (8): 944-950. DOI:

https://doi.org/10.1002/alr.22587

Muntner P, Shimbo D, Carey RM, Charleston

JB, Gaillard T et al. (2019) Measurement

of blood pressure in humans: a scientific

statement from the American Heart

Association. Hypertension 73 (5): e35-

e66. DOI:

https://doi.org/10.1161/HYP.000000000

Parascandola M, & Xiao L (2019) Tobacco and

the lung cancer epidemic in China.

Translational lung cancer research 8

(Suppl 1): S21. DOI:

https://doi.org/10.21037%2Ftlcr.2019.03

.12

Patanavanich R, & Glantz SA (2020) Smoking is

associated with COVID-19 progression: a

meta-analysis. Nicotine and tobacco

research 22 (9): 1653-1656. DOI:

https://doi.org/10.1093/ntr/ntaa082

Peng X, Xu X, Li Y, Cheng L, Zhou X et al. (2020)

Transmission routes of 2019-nCoV and

controls in dental practice. International

journal of oral science 12 (1): 1-6. DOI:https://doi.org/10.1038/s41368-020-

-9

Piva S, Filippini M, Turla F, Cattaneo S, Margola

A et al. (2020) Clinical presentation and

initial management critically ill patients

with severe acute respiratory syndrome

coronavirus 2 (SARS-CoV-2) infection in

Brescia, Italy. Journal of critical care 58:

-33. DOI:

https://doi.org/10.1016/j.jcrc.2020.04.00

Rambaut A, Holmes EC, O’Toole A, Hill V,

McCrone JT et al. (2020) A dynamic

nomenclature proposal for SARS-CoV-2

lineages to assist genomic epidemiology.

Nature microbiology 5 (11): 1403-1407.

DOI: https://doi.org/10.1038/s41564-

-0770-5

Rodriguez-Morales AJ, Bonilla-Aldana DK, BalbinRamon GJ, Rabaan AA, Sah R et al. (2020)

History is repeating itself: Probable zoonotic

spillover as the cause of the 2019 novel

Coronavirus Epidemic. InfezMed 28 (1): 3-5.

URL:

https://www.researchgate.net/publication/33

Salehi S, Abedi A, Balakrishnan S, &

Gholamrezanezhad A (2020) Coronavirus

disease 2019 (COVID-19) imaging

reporting and data system (COVID¬

RADS) and common lexicon: a proposal

based on the imaging data of 37 studies.

European radiology 30: 4930-4942. DOI:

https://doi.org/10.1007/s00330-020-

-0

She J, Jiang J, Ye L, Hu L, Bai C et al. (2020) 2019

novel coronavirus of pneumonia in

Wuhan, China: emerging attack and

management strategies. Clinical and

translational medicine 9 (1): 1-7. DOI:

https://doi.org/10.1186/s40169-020-

-z

Wang CC, Prather KA, Sznitman J, Jimenez JL,

Lakdawala SS et al. (2021) Airborne

transmission of respiratory viruses. Science

(6558): eabd9149. DOI:

https://doi.org/10.1126/science.abd9149

Wang F, Nie J, Wang H, Zhao Q, Xiong Y et al.

(2020) Characteristics of peripheral

lymphocyte subset alteration in COVID-

pneumonia. The Journal of infectious

diseases 221 (11): 1762-1769. DOI:

https://doi.org/10.1093/infdis/jiaa150

Wong HYF, Lam HYS, Fong AH-T, Leung ST,

Chin TW-Y et al. (2020) Frequency and

distribution of chest radiographic findings

in patients positive for COVID-19.

Radiology 296 (2): E72-E78. DOI:

https://doi.org/10.1148/radiol.20202011

Wu Z, & McGoogan JM (2020) Characteristicsof and

important lessons from the coronavirus

disease 2019 (COVID-19) outbreak in China:

summary of a report of 72 314 cases from the

Chinese Center for Disease Control and

Prevention. Jama 323 (13): 1239-1242. DOI:

https://doi.oig/10.1001/iama.2020.2648

Xu X, Han M, Li T, Sun W, Wang D et al. (2020)

Effective treatment of severe COVID-19

patients with tocilizumab. Proceedings of the

National Academy of Sciences 117 (20):

-10975. DOI:

https://doi.oig/10.1073/pnas.20Q5615117

Xu Y, Li X, Zhu B, Liang H, Fang C et al. (2020)

Characteristics of pediatric SARS-CoV-2

infection and potential evidence for

persistent fecal viral shedding. Nature

medicine 26 (4): 502-505. DOI:

https://doi.org/10.1038/s41591-020-

-4

Yang W, Cao Q, Qin L, Wang X, Cheng Z et al.

(2020) Clinical characteristics and

imaging manifestations of the 2019 novel

coronavirus disease (COVID-19): a multi¬

center study in Wenzhou city, Zhejiang,China. Journal of Infection 80 (4): 388-

DOI:

https://doi.Org/10.1016/j.jinf.2020.02.01

Zhang J-j, Dong X, Cao Y-y, Yuan Y-d, Yang Yb et al. (2020) Clinical characteristics of

patients infected with SARS CoV 2 in

Wuhan, China. Allergy 75 (7): 1730-1741.

DOI: https://doi.Org/10.l111/all.14238

Zhao W, Zhong Z, Xie X, Yu Q, & Liu J (2020)

Relation between chest CT findings and

clinical conditions of coronavirus disease

(COVID-19) pneumonia: a multicenter

study. Ajr Am J Roentgenol 214 (5): 1072-

DOI:

https://doi.org/10.2214/AJR.20.22976

Zhu J, Zhong Z, Li H, Ji P, Pang J et al. (2020)

CT imaging features of 4121 patients with

COVID 19: a meta analysis. Journal of

medical virology 92 (7): 891-902. DOI:

https://doi.org/10.1002/jmv.25910

Zhu Z, Cai T, Fan L, Lou K, Hua X et al. (2020)

Clinical value of immune-inflammatory

parameters to assess the severity of

coronavirus disease 2019. International

Journal of Infectious Diseases 95: 332-

DOI:

https://doi.Org/10.1016/j.ijid.2020.04.04

Zietsman M, Phan LT, & Jones RM (2019)

Potential for occupational exposures to

pathogens during bronchoscopy

procedures. Journal of occupational and

environmental hygiene 16 (10): 707-716.

DOI:

https://doi.Org/10.1080/15459624.2019.l

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2023-02-28

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Ala Hussian, H., Fadhil Kadhim Jasim , A., & Usama Khalaf, M. (2023). Relationship between CT-finding, degree of lung involvement and oxygen saturation in hospitalized patients with COVID19. History of Medicine, 9(1). http://13.200.237.241/HOM/index.php/medicine/article/view/506