Comparison Of Efficacy of Beclomethasone Inhaler and Topical Lidocaine in Reducing Postoperative Complications of Endotracheal Intubation in Patients Undergoing Major Selective Surgeries

Authors

  • Afzal Shamsi Department of Anesthesia, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran. Nursing and Midwifery Care Research Center, Tehran University of Medical Sciences, Tehran, Iran. Author
  • Zainab Hashim Aziz Almusawi Iraqi bord of anasthesia M.B.Ch. B / FICMS A&IC bint-alhuda teaching hospital for obstetrics and pediatric surgery —head of department of aneasthesia and ICU Author
  • Mojgan Rahimi Departmen of Anesthesiology and Critical Care, Associated Professor, Tehran University of Medical Sciences, Tehran, Iran Author
  • Hossein Majedi MD, AFSA Associated Professor, Pain research center, Neuroscience Institute, Imam Khomeini Hospital Complex, Anesthesiology and Pain Medicine, Tehran University of Medical Sciences. Tehran, Iran. Author
  • Hussein Zayed Kareem Student of Anesthesia Technology, Department of Anesthesia, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran. Author

Keywords:

Beclomethasone, Lidocaine, Sore Throat, Cough, Hoarseness, Tracheal Intubation.

Abstract

Sore throat, cough and hoarseness of voice are common problems after endotracheal general anesthesia. They may be very distressing to the patient and they may have many unwanted sequelae. Various preparations of lidocaine and corticosteroids have been frequently used to prevent or attenuate these complications. The aim of this study to compare the effect of lidocaine lubricant gel (on endotracheal tube) and beclomethasone inhalation preoperatively on the incidence and severity of postoperative sore throat, cough, and hoarseness of voice.   This study included 90 patients (20-35 years of age) male patients undergoing elective major surgeries with ASA physical status I were randomized into three groups of 30 patients as follows (group A: Topical lidocaine, group B: Beclomethasone inhaler, group C: Control). The endotracheal tubes in group (A)were lubricated with lidocaine gel 5%. Group (B) patients receive 2 puffs (100 ug) of beclomethasone inhaler. In the group C patients, no medication was administered or applied. Patients were interviewed by a blind investigator for sore throat, cough and hoarseness (as none, mild, moderate, or severe), at 2 h, 6 h, 12 h, and 24 h after full recovery. 

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References

Smetana G. Preoperative Pulmonary Evaluation. New England Journal

of Medicine.1999 Mar ;340(12):937-944.

Rock P, Rich P. Postoperative pulmonary complications. Current

Opinion in Anaesthesiology. 2003Apr ;16(2):123-131.

Navarro RM, Baughman VL. Lidocaine in the endotracheal tube cuff

reduces postoperative sore throat. Journal of Clinical

Anesthesia.1997 Aug ; 9(5): 394-397.

Tanaka Y, Nakayama T, Nishimori M, Tsujimura Y, Kawaguchi M, Sato

Y. Lidocaine for preventing postoperative sore throat. The

Cochrane Collaboration. 2015 Jul:1-40.

McHardy F, Chung F. Postoperative sore throat: cause, prevention, and

treatment. Anesthesia. 2002 Apr ;54(5):444-453.

Macario A, Weinger M, Carney S, Kim A. Which Clinical Anesthesia

Outcomes Are Important to Avoid? The Perspective of Patients.

Anesthesia & Analgesia. 1999 Sep ;89(3):652.

Agarwal A, Nath S, Goswami D, Gupta D, Dhiraaj S, Singh P. An

Evaluation of the Efficacy of Aspirin and Benzydamine

Hydrochloride Gargle for Attenuating Postoperative Sore Throat: A

Prospective, Randomized, Single-Blind Study. Anesthesia &

Analgesia. 2006 Oct ;103(4):1001-1003.

Park H, Im J, Park J, Joe J, Lee S, Yon J et al. A comparative evaluation

of humidifier with heated wire breathing circuit under general

anesthesia. Korean Journal of Anesthesiology. 2009 Jul.;57(1):32.

Branson R, Campbell R, Davis K, Porembka D. Anesthesia Circuits,

Humidity Output, and Mucociliary Structure and Function.

Anesthesia and Intensive Care. 1998 Apr ;26(2):178-183.

Christensen A, Willemoes-Larsen H, Lundby L, Jakobsen K.

Postoperative throat complaints after tracheal intubation. British

Journal of Anesthesia.1994;73(6):786-787.

Harding C, McVey F. Interview method affects the incidence of

postoperative sore throat. Anesthesia. 1987;42(10):1104-1107.

Herlevsen P, Bredahl C, Hindsholm K, Kruhoffer P. Prophylactic

laryngo-tracheal aerosolized lidocaine against postoperative sore

throat. Acta Anesthesiologica Scandinavica. 1992 Aug ;36(6):505-

Jorgensen L, Weber M, Pedersen A, Munster M. No increased incidence

of postoperative sore throat after administration of suxamethonium

in endotracheal anesthesia. Acta Anesthesiologica Scandinavica.

Nov;31(8):768-770.

Winkel E, Knudsen J. Effect on the Incidence of Postoperative Sore

Throat of 1 Percent Cinchocaine Jelly for Endotracheal Intubation.

Anesthesia & Analgesia. 1971Jan;50(l):92-94.

Dingley J, Whitehead M, Wareham K. A comparative study of the

incidence of sore throat with the laryngeal mask airway. Anesthesia.

Mar;49(3):251-254.

Keller C, Sparr H, Brimacombe J. Laryngeal mask lubrication.

Anesthesia. 1997 Jun;52(6):593-597.

Wakeling H, Butler P, Baxter P. The Laryngeal Mask Airway: a

comparison between two insertion techniques. Anesthesia &

Analgesia. 1997 Sep;85(3):687-690.

Blanc V, Tremblay N. The Complications of Tracheal Intubation.

Anesthesia & Analgesia. 1974 Mar;53(2):202-213.

Widdicombe J. Neurophysiology of the cough reflex. European

Respiratory Journal. 1995;8(7):1193-1202.

Camacho Navarro L, Moreira e Lima R, Simoes Aguiar A, Cerqueira

Braz J, Carness J, Pinheiro Modolo N. The effect of intracuff

alkalinized 2% lidocaine on emergence coughing, sore throat, and

hoarseness in smokers. Revista da Associate Medica Brasileira.

Mar;58(2):248-253.

Abbasi, S., Mahjobipoor, H., Kashefi, P., Massumi, G., Aghadavoudi, O.,

Farajzadegan, Z., & Sajedi, P. The effect of lidocaine on reducing

the tracheal mucosal damage following tracheal intubation. Journal

of research in medical sciences.2013 Sep;18(9), 733-738.

Leech P, Barker J. Fitch W.Changes in intracranial pressure and

systemic arterial pressure during the termination of anesthesia.

British Journal of Anesthesia. 1974 Apr;46(4):315-316.

Bidwai A, Bidwai V, Rogers C, Stanley T. Blood-pressure and Pulse-rate

Responses to Endotracheal Extubation with and without Prior

Injection of Lidocaine. Anesthesiology. 1979;51(2):171-172.

Jones G, Hale D, Wasmuth C, Homi J, Smith E, Viljoen J. A survey of

acute complications associated with endotracheal intubation.

Cleveland Clinic Journal of Medicine. 1968;35(1):23-31.

Baron S, Kohlmoos H. LXIX Laryngeal Sequelae of Endotracheal

Anesthesia. Annals of Otology, Rhinology & Laryngology. 1951

Sep;60(3):767-792.

Kambic V, Radsel Z. Intubation lesions of the larynx. British Journal of

Anesthesia. 1978 Jun;50(6):587-590.

Stein A, Quebral R, Boba A, Landmesser C. A post mortem evaluation

of laryngotracheal alterations associated with intubation. Survey of

Anesthesiology. 1961 Jan;5(4):359.

Hahn F, Martin J, Lillie J. Vocal-Cord Paralysis With Endotracheal

Intubation. Archives of Otolaryngology - Head and Neck Surgery.

Sep;92(3):226-229.

Tonkin J, Harrison G. The surgical management of the laryngeal

complications of prolonged intubation. The Laryngoscope. 1971

Feb;81(2):297-307.

Alessi D, Hanson D, Berci G. Bedside Videolaryngoscopic Assessment

of Intubation Trauma. Annals of Otology, Rhinology &

Laryngology. 1989 Aug;98(8):586-590.

Mencke T, Echternach M, Kleinschmidt S, Lux P, Barth V, Plinkert P et

al. Laryngeal Morbidity and Quality of Tracheal Intubation.

Anesthesiology. 2003 May;98(5):1049-1056.

Letizia, Marijo; O'Leary, Jennifer; Vodvarka, Jane. Laryngeal edema:

perioperative nursing considerations. Medsurg Nursing. 2003 Apr

;12(2):111-115.

Stride P. Postoperative sore throat: topical hydrocortisone. Anesthesia.

Nov;45(ll):968-971.

Takekawa K, Yoshimi S, Kinoshita Y. Effects of intravenous lidocaine

prior to intubation on postoperative airway symptoms. Journal of

Anesthesia. 2006 Feb;20(l):44-47.

Sumathi P, Shenoy T, Ambareesha M, Krishna H. Controlled

comparison between betamethasone gel and lidocaine jelly applied

over the tracheal tube to reduce postoperative sore throat, cough,

and hoarseness of voice. Br J Anesthesia. 2008 Feb; 100(2):215-218.

Choi YH, Ji SM, Yoon SH, Park SI. Comparison of postoperative sore

throat due to cuff inflation of the endotracheal tube using the pilot

balloon palpation technique and the minimally occlusive volume

technique during total laparoscopic hysterectomy. Anesthesia and

Pain Medicine. 2011 Oct;6(4):380-384.

Higgins PP, Chung F, Mezei G. Postoperative sore throat after

ambulatory surgery. Br J Anaesth 2002 Apr; 88: 582-4.

Elhakim M, Ali NM, Rashed I, Riad MK, Refat M. Dexamethasone

reduces postoperative vomiting and pain after pediatric

tonsillectomy. Can J Anaesth 2003; 50: 392-7.

Yukioka H, Yoshimoto N, Nishimura K, Fujimori M. Intravenous lidocaine as a suppressant of coughing during tracheal intubation in elderly patients. Anesthesia and Analgesia 1985 Dec; 64(12): 1189-1192.

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Published

2023-04-30

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How to Cite

Shamsi, A., Hashim Aziz Almusawi, Z., Rahimi, M., Majedi, H., & Zayed Kareem, H. (2023). Comparison Of Efficacy of Beclomethasone Inhaler and Topical Lidocaine in Reducing Postoperative Complications of Endotracheal Intubation in Patients Undergoing Major Selective Surgeries. History of Medicine, 9(2). http://13.200.237.241/HOM/index.php/medicine/article/view/490