Role of IL-24, IL-29, IL -31 in Rheumatoid arthritis patients
Keywords:
Rheumatoid arthritis, IL-24, IL-29, IL-31.Abstract
This study was conducted during the period 23/8/2022 to 30/1/2023 in order to identify the role of IL-24, IL-29, IL-31 in patients with rheumatoid arthritis in Al-Diwaniyah city. The results showed: ESR and BMI values were significantly elevated in patients with rheumatoid arthritis compared to healthy persons. The incidence of rheumatoid arthritis was significantly raised in women compared to men. Body mass index had a significant influence on the incidence of rheumatoid arthritis, while age did not significantly affect the incidence of rheumatoid arthritis. The average levels of IL-24, IL-29 and IL-31 were (138.323, 152.997 and 80.731) ng/L respectively in blood serum of patients with rheumatoid arthritis, compared to (91.026, 100.402 and 57.257) ng/L respectively in blood serum of healthy persons. The level of IL-24, IL-29 and IL-31 increased significantly (P < 0.01) in rheumatoid arthritis patients compared to healthy persons. The values of correlation coefficients ranged between ESR, IL-24, IL-29, IL-31 (0.634 and 0.735) and were highly significant. Sex did not have a significant effect on the level of interleukins, age did not have a significant effect except for IL-31, and body mass index did not have a significant effect in healthy persons. Sex had no significant influence on the level of interleukins, age also had no significant effect, and body mass index had no significant effect except for IL-24 in patients with rheumatoid arthritis.
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